Cognition Peptides

Neuroactive Research Peptides with Dual Quality Verification

This cluster combines three biochemically distinct neuropeptides used in preclinical research on dopaminergic, serotonergic, and neuroendocrine issues: Semax, a synthetic ACTH(4-10) fragment; Selank, a tuftsin analog; and DSIP (Delta Sleep-Inducing Peptide), a nonapeptide of neuroendocrine origin, which is being investigated in preclinical research in the context of sleep-wake regulation.

Each EONA batch undergoes a two-stage analytical verification: a batch-specific commercial COA (HPLC purity >=98%, MS-confirmed identity) and an independent academic counter-check of the same batch. Both certificates can be viewed before ordering. Shipping is from the EU warehouse, without third-country customs risk. Volume discount: 1, 3, 5, or 10 vials with up to 30% savings for research laboratories. For research purposes only.

Frequently Asked Questions

What HPLC purity should Semax and Selank have for preclinical in vitro research?

For reliable in vitro work, a purity of at least 98% by HPLC is cited in the literature as a minimum standard. All EONA batches are tested to this value; the result is documented in the batch-specific COA, which can be downloaded before ordering. In addition, an independent academic counter-check confirms purity and identity by mass spectrometry.

What is the difference between a commercial manufacturer's COA and an independent academic counter-check?

A commercial manufacturer's COA is created by the producing laboratory and tests purity and identity as part of its own quality assurance. An independent academic counter-check means that a second analytical instance, separate from the manufacturer, re-measures the same batch. EONA combines both procedures: commercial batch COA plus academic counter-check. The procedure is described on the Verification: two-stage procedure page.

Can Semax be ordered in Germany for research purposes, and what is the legal classification of Selank and DSIP?

Semax and Selank are not approved as medicinal products in Germany and are not subject to the BtMG or the NpSG; as research substances, they can be obtained by verified research institutions and qualified private individuals. DSIP is legally classified analogously as an unapproved research substance but is not yet available for purchase in the EONA product range. EONA sells exclusively for research purposes, not for human use. When sourcing from the EU warehouse, the customs risk of a third-country import is eliminated. For specific legal questions, examination by a lawyer is recommended.

How do Semax, Selank, and DSIP differ biochemically and in their preclinical research direction?

Semax is a synthetic heptapeptide, derived from the ACTH(4-10) fragment, and is investigated in preclinical research in the context of dopaminergic and serotonergic signaling pathways. Selank is a tuftsin analog (octapeptide) and is the subject of preclinical studies on GABAergic and serotonergic regulatory circuits. DSIP (Delta Sleep-Inducing Peptide) is a nonapeptide of neuroendocrine origin and is investigated in preclinical research in the context of sleep-wake regulation. In preclinical literature, Semax and Selank are sometimes considered together in the context of serotonergic signaling pathways, while DSIP is assigned to the neuroendocrine axis. All three substances are available as lyophilized solids. DSIP is not yet available for purchase in the EONA product range.

What storage conditions apply to lyophilized neuropeptides as research material?

Lyophilized research peptides should be stored cool (2-8 °C), dry, and protected from light. Unopened vials are typically stable for months under these conditions; exact details can be found in the respective COA and product data sheet. Storage at -20 °C generally further extends stability. EONA explicitly does not provide reconstitution or application instructions.

Why is a batch-specific COA preferable to a general product specification?

A general product specification describes the target nominal value, not the actual measured result of the batch supplied. A batch-specific COA proves the measured purity value and the mass spectrometrically confirmed identity of exactly the batch that the researcher receives. This makes the quality of the substance directly traceable for the respective experiment. EONA provides the COA per batch; the academic counter-check forms the second verification stage. Learn more in the guide Reading a COA: Step by Step.

Further research peptides from European sources can be found in the clusters Verified Peptides from Europe and Longevity Peptides. All substances in the cognition cluster are for research purposes only.